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Mark's hands are 20 times bigger than a normal adult male's; after learning that his condition may require amputation, Mark stopped seeing doctors; now troubling changes to his hands means he must go back.
Life defined by height: in Turkey, the world's tallest woman lives with an unknown genetic condition linked to extreme growth and fragile bones, while in Brazil, the world's shortest couple navigate dwarfism and its physical challenges.
In Brazil, Claudio lives with a condition that bent his head backward; ahead of his 50th birthday, he wants to climb a sacred mountain; in Norway, Birgitte is training for the next Paralympics.