Ruthless drug lord Pablo Escobar turns Columbia into the murder capital of the world and may have been responsible for 4,000 to 5,000 murders.
David Berkowitz, aka the Son of Sam, goes on a yearlong murderous rampage killing six people in 1976 and bringing New York City to its knees.
Known as the Boston Strangler, Albert DeSalvo's murder spree claims the lives of 13 women, many of whom he strangled to death with their own nylon stockings.
Police officer turned killer Laurie Bembenek is convicted of murdering her husband's ex-wife, Christine Schultz; Bembenek claims she was framed for the savage murder, but the evidence included her husband's police revolver and fibers from her wig.
On the FBI's Most Wanted list for more than a decade, Al Qaeda founder Osama Bin Laden orchestrates an attack against the United States, using 19 militants to hijack four airplanes with which to carry out suicide missions on Sept. 11, 2001.