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With college in sight, Sheldon is determined to ride his bike without training wheels; Mary and George Sr. argue over parenting styles.
Sheldon finds himself in a fierce competition with Paige when their mothers force them to attend Vacation Bible School; George is furious after Georgie makes a questionable purchase.
Dale and Meemaw work out relationship issues while playing Dungeons and Dragons with Sheldon and Missy; Mary and George take a trip with coach Wilkins and his wife; Georgie's girlfriend thinks she's pregnant.
College orientation does not go as Sheldon planned; Mary is invited to a party when she's mistaken for a university student; George Sr. helps Pastor Jeff set up a children's nursery.
Sheldon's first day of college is derailed by his new philosophy teacher, professor Ericson; Mary and Brenda live vicariously through Missy's first day of middle school.
Meemaw takes matters into her own hands when Sheldon's philosophy teacher sends him into a tailspin; George Sr. learns Georgie has been cutting class.
Sheldon and George Sr. have dinner with President Hagemeyer and a university benefactor; Georgie gives Missy some brotherly advice when Mary won't let her go to the school dance; Dale and June convince Meemaw to attend their son's wedding.
Sheldon campaigns to become Dr. Linkletter's lab assistant; Georgie enlists the help of Mr. Lundy, the drama teacher, for a business venture.
Dr. Linkletter pushes Sheldon to make friends with his fellow students at college; Georgie gets a pager.
Sheldon, Dr. Linkletter and Meemaw team up on a science experiment; Mary is jealous that Pastor Jeff and Brenda are spending time together; Georgie has a new side hustle.