Charles "Lucky" Luciano teams up with Meyer Lansky and Bugsy Siegel in New York, and during prohibition, he makes a fortune.
"Lucky" Luciano takes over the mob, organizing the Five Families, but as his power increases, so does interest from the Feds.
"Lucky" Luciano decides to go into the prostitution business, but it gives Thomas Dewey the opportunity to arrest him and put him on trial.
"Lucky" Luciano is found guilty of running a prostitution ring, and is imprisoned; Vito Genovese becomes acting boss.
As World War II begins, Charles "Lucky" Luciano is asked to aid the military in the invasion of Sicily; Dewey considers allowing Luciano to fight.
Luciano takes over Vito Genovese's heroin ring in Italy; Genovese and Gambino plot against mob leadership.
Vito Genovese and Carlo Gambino make their move; when Genovese becomes a liability, Luciano must choose his successor.