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One local teacher, Louisa Gavin, questions Martin's harsh demeanor; Martin quickly gets annoyed by the antics of the town locals.
After Martin comes face to face with his childhood bully and diagnoses a potentially contagious illness, he is forced to cancel Port Wenn's monthly baked bean supper, angering everyone in the town.
On the eve of Port Wenn High School's baseball team's playoff game, the town is furious with Martin when he accidentally breaks the arm of their star player; Elaine moves into Martin's waiting room after fighting with her mom.
Port Wenn's favorite hunky wilderness survival instructor goes missing after Martin deduces that he desperately needs medical help; the locals are furious with Martin after he calls the health inspector about a suspected food poisoning.
While conducting a wellness check on the agoraphobic recluse who controls the town power grid, Martin's brusque bedside manner ultimately causes a massive town black out.
On the eve of Port Wenn's annual blueberry festival, Martin treats a local man who has apparently become blue from eating too many blueberries; Martin is disturbed by Aunt Sarah's lack of attention to her health.
When Port Wenn puts on their annual "Blood Factory," celebrating the gory horror novel set there, Martin must contain his secret debilitating blood phobia when Louisa gets seriously ill and needs his help.
Port Wenn goes into high alert when a corpse is found in the town's bog and Martin's autopsy reveals that he was murdered; Martin's solo investigation trek leads him to a startling discovery about himself.
When Martin's parents make a surprise visit, Martin suspects that his father is experiencing a serious health condition; Louisa is made acting principal; Martin and Robert must operate together on Mark.
Martin invites Louisa to watch the annual bird migration over Port Wenn;an elderly woman has hallucinations that lead to dire consequences; Martin must perform an emergency procedure on his young friend.
Port Wenn goes on lockdown when a patient with fleas sparks fears of a plague outbreak; Martin must deal with the town gossip when it revolves around him and Louisa; Aunt Sarah feels betrayed by Greg and George; Louisa has an epiphany.
Martin is skeptical when Port Wenn welcomes a friendly delegation from their sister city in Norway; Louisa visits a specialist who just happens to be Martin's ex; Greg believes that he is pooping little men; Mark exhibits troubling symptoms.
Martin must toggle between the potential revelation of his blood phobia, a startling baby delivery and the arrival of his amorous ex; Louisa receives some thought-provoking medical results; Al and Elaine must navigate their uncertain future.